Low White Blood Cell Count And Fatigue – Low white blood cell count is a condition in which the number of white blood cells in the body is too low. White blood cells (also called leukocytes) are part of the immune system and are cells that protect the body from infection by bacteria, viruses, fungi, and parasites. A decrease in the number of white blood cells is also known as leukopenia.

White blood cells are very important for health. Life is impossible without them. Disease-causing microorganisms are literally everywhere, but most people don’t get sick because their white blood cells have enough defenses. A low white blood cell count is not considered normal, as it often means there is a problem with your body.

Low White Blood Cell Count And Fatigue

There are several types of white blood cells. Each has its own special purpose and different lifespan. Monocytes (which transform into other white blood cells), lymphocytes (which release antibodies, regulate immunity, and kill infected human cells), basophils (initiate an inflammatory response), and eosinophils (which kill parasites) neutrophils (the leading cause of death in humans). bacteria and fungi).

Low Blood Counts

Our bodies continually produce millions of different white blood cells to replace those that are worn out or dead. Therefore, the number remains relatively stable most of the time. The immune system skillfully regulates the number of active white blood cells, increasing or decreasing the number of certain types depending on the situation. In moments where you put yourself at risk, such as by eating dirty or rotten food, breathing in microbial-laden dust, staying in crowded places, or being in places like airplanes, gyms, and hospitals. Even if we do, we often don’t get sick. Adequate supply of white blood cells that kill pathogens before they can cause infection.

When we become ill, our immune system initiates a series of actions to stop or kill invading pathogens and destroy infected or dying cells in the body. Infections often cause a rapid increase in white blood cell counts. Your doctor can easily tell if you have an infection by seeing that your white blood cell count is higher than normal. When white blood cells increase, the body is more likely to fight off an infection.

Of course, your white blood cell count may also decrease. Most cases are associated with health problems, some of which are serious, and require thorough investigation. A low white blood cell count is not a diagnosis or a health condition. It’s just the result of a routine blood test.

The correct term for the blood test or test is a complete blood count or CBC. Doctors often order a CBC to analyze the number of cellular components, including white blood cells. Normal thresholds for white blood cell counts may vary. The Mayo Clinic states that the normal range is 3.5 billion to 10.5 billion cells per liter of blood. Meanwhile, MEDLINE Plus states that a normal white blood cell count is between 4,500 and 11,000 per microliter (mcL).

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CBC is the only way to measure the number of white blood cells in your body. Your doctor may order some CBC tests to monitor your blood cell counts.

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The main purpose of white blood cells is to protect the body from infection by microorganisms. If that number gets too low, you may be more susceptible to infections. In fact, most people do not experience symptoms unless their white blood cell count becomes very low.

If your white blood cell count has been low for some time, you may get sick or have infections more often than usual.

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All microorganisms except HIV cannot attack white blood cells directly. On the other hand, the main purpose of white blood cells is to kill microorganisms. Also, when an infection or inflammation occurs, the body naturally produces more white blood cells. This explains why infections cause an increase in white blood cell counts.

As mentioned before, our bodies continually produce white blood cells. White blood cells, like other components of blood, are produced in the bone marrow. A low blood cell count means that there is something wrong with the production of white blood cells.

In most cases, a low white blood cell count is the result of a disease. Depending on the treatment, it may also occur as a side effect. Malnutrition or nutrient deficiencies can also cause low white blood cell counts.

A low white blood cell count is often associated with illness. The most common cause is a serious infection, which can deplete white blood cells faster than they can be produced. If the disease is not treated or does not respond to treatment, a severe infection can develop. It often occurs in infants, young children, and the elderly.

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A low white blood cell count is often a hallmark of immunodeficiency or a weakened immune system. As we learned in school, white blood cells are the workhorses of the immune system. Low counts of certain white blood cells in the CBC often reveal the cause of immunodeficiency. The most common conditions that cause immunodeficiency include systemic lupus erythematosus (lupus), tuberculosis, dengue virus infection, rickettsiae, psittacosis, Sjögren’s syndrome, Lyme disease, and Hodgkin’s lymphoma.

HIV infection is also a common cause of low white blood cell counts. The human immunodeficiency virus primarily targets CD T4 helper cells, the precise cells that prime the immune system against infection. HIV reduces the number of white blood cells over time. When the white blood cell count gets too low, opportunistic bacteria and viruses can enter the body and cause infections, resulting in many of the serious health problems that define AIDS. Diagnosed or undiagnosed HIV infection is a very common cause of low white blood cell counts in both developed and developing countries.

A condition called sarcoidosis can also cause a large number of white blood cells to malfunction. Sarcoidosis is an inflammatory disease characterized by the formation of lumps called granulomas in the lungs, skin, or lymph nodes. The cause of sarcoidosis is often unknown, but doctors suspect that it may be caused by problems with the immune system. Granulomas in the lungs can be caused by an immune response to something inhaled into the lungs. Sarcoidosis may not cause any symptoms. It is often discovered after a chest x-ray. In most cases, sarcoidosis resolves on its own without treatment.

Septic shock is a condition caused by a severe infection that causes widespread and destructive inflammation throughout the body, often resulting in a significant drop in white blood cells. In some cases of sepsis, the white blood cell count can be very low, sometimes as low as 4,000 cells per microliter.

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Viruses can infect the bone marrow and reduce the production of white blood cells, resulting in a low blood cell count. Bone marrow infections are rare but can occur due to infection of the bloodstream or injuries near bones (including bedsores). Some of these viruses cause diseases such as parobovirus B19, dengue fever, hepatitis virus, Epstein-Barr virus, cytomegalovirus, and human immunodeficiency virus.

In cancer patients, low white blood cell counts are often caused by chemotherapy. Drugs used to treat cancer work by killing the rapidly dividing cells that make up tumors. The problem is that cells in the bone marrow also divide very quickly, making them a target for chemotherapy drugs as well. Radiation therapy used to kill cancer cells also destroys bone marrow, causing a drop in white blood cell counts. During cancer treatment, your doctor will order several CBC tests to monitor your white blood cells and try to make sure they don’t drop too low. Your health care provider will also monitor you for signs of infection.

Some cancers can also damage the bone marrow and affect white blood cells. This can happen with any cancer if it affects the bones. A particular type of cancer called acute myeloid leukemia starts in the bone marrow and can affect the cells that produce white blood cells. Multiple myeloma, another cancer, also causes a decrease in white blood cells because it interferes with the production of blood components.

Another cause is a genetic or congenital problem that causes decreased bone marrow function, also called hereditary bone marrow failure. It is caused by genetic problems. For some of these diseases, symptoms may not appear until adulthood. These conditions include Fanconi anemia, dyskeratosis congenita, Shwachman-Diamond syndrome, Diamond-Blackfan anemia, severe congenital neutropenia, and congenital amegakaryocytic thrombocytopenia. Masu. The good news is that this situation is relatively rare.

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A low white blood cell count may be caused by taking certain antibiotics. This is a reported side effect of many penicillins and cephalosporins, including penicillin G, cefazolin, cefoxitin, and cephalothin. Relatively rare.

When white blood cell levels are low, the focus of treatment is to prevent infection. A low white blood cell count also means that your defenses against infection are low. Need to stick to seemingly simple but important things

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