Function Of Vitamin B1 In The Body – Note: ThePregistry website includes expert reports on more than 2000 drugs, 300 diseases, and 150 common manifestations during pregnancy and lactation. For the topic

We have talked a lot about vitamin D and about vitamins in general during pregnancy, but not so much about thiamine deficiency (thiamin), also known as vitamin B1, and about this vitamin deficiency, so let’s make thiamine deficiency our topic for today. Thiamine deficiency can develop for many reasons, including alcoholism (this is quite common) and lack of thiamine in the diet. There is also an important connection between thiamine deficiency and diabetes, because of the role thiamine plays in the metabolism of sugar. During pregnancy, your need for thiamine increases, and thiamine deficiency can develop as a complication of hyperemesis gravidarum (HG), a condition with severe nausea and vomiting, weight loss and liver problems.

Function Of Vitamin B1 In The Body

Apart from alcoholics, thiamine deficiency is rare in the developed world, but thiamine deficiency in food is associated with certain diets, especially diets dominated by refined rice in developing countries. However, thiamine deficiency is possible in developed countries that follow the popular “gluten-free” diet, which avoids all grains (a good source of thiamine) is suitable, only for those who suffer from celiac disease, but not for everyone. Other. Other factors that put you at risk of thiamine deficiency include HIV/AIDS, bariatric surgery, diuretics (drugs that increase the excretion of water through the kidneys). Type 2 diabetes, which is characterized by the body’s decreased ability to respond to insulin, increases the need for thiamine, so it is a cause of thiamine deficiency and the condition that thiamine deficiency can worsen.

Pregnancy And Thiamine (vitamin B1) Deficiency

Mild thiamine deficiency is very difficult to diagnose, because the symptoms are mild and not specific to the condition. Therefore, the index of suspicion for thiamine deficiency is often very low for non-alcoholics, so doctors have no reason to order tests, such as thiamine levels in the blood and urine. As the deficiency worsens, however, the symptoms develop into a common feature of the disease called beriberi, which is characterized by symptoms related to the nervous system and the cardiovascular system. In addition, various metabolic disorders often occur, including lactic acidosis. A combination of effects suggests a possible thiamine deficiency, leading to testing for thiamine levels in blood and urine samples. Most importantly, thiamine deficiency can be assessed by measuring the activity of an enzyme called erythrocyte transketolase (EKTA), which requires thiamine to work, and it is important for the biochemical link that breaks down sugar (blood sugar) to release energy through this pathway. Create various biochemical compounds from sugar. Therefore, if EKTA activity is low, this supports the diagnosis of thiamine deficiency.

Symptoms of beriberi include tingling (paresthesia) and loss of sensation (numbness) in the hands and feet, shortness of breath, vomiting, and cardiovascular problems that may include rapid heartbeat and accumulation of fluid throughout the body (edema). In the end, cardiovascular effects (commonly known as “wet beriberi”) can lead to heart failure, and neurological effects (“dry beriberi”) can reach the point of two very serious complications. This complication is called Wernicke encephalopathy (WE). Usually triggered by the administration of intravenous fluid containing glucose (sugar), WE is characterized by three neurological abnormalities, all of which occur in most cases: one is the weakness of the muscles that move the eye (ophthalmoparesis) with rapid, repetitive movements. Eyes back and forth (nystagmus). Another disorder is the lack of full control of voluntary muscles and coordinated body movements (ataxia) and the third disorder is confusion. Other neurological complications are Korsakoff’s syndrome, which is a mental illness that begins with memory loss, followed by what is called

, in which a person unwittingly invents information to fill in the memory gap. The combination of WE syndrome and Korsakoff syndrome is known as Wernicke-Korsakoff syndrome (WKS).

For children, thiamine deficiency increases the risk of adverse pregnancy outcomes, including spontaneous abortion (miscarriage), fetal death, and stillbirth. However, thiamine deficiency is easily treated with 50-100 mg of thiamine administered intravenously (IV) and then a small dose (eg 10 mg) injected intramuscularly (IM) daily for a week. Thiamine therapy must begin before the woman receives glucose (dextrose). Otherwise, it is very dangerous that glucose can cause the development of WE.

Benefits Of B1 + Signs Of Thiamine Deficiency

As in the case of pregnancy, breastfeeding increases the need for thiamine, due to the need for thiamine of the baby. Rather than being a risk for nursing babies, thiamine supplementation is important to ensure that your milk provides your baby with enough thiamine. If your doctor determines that your thiamine status is poor, you may need to feed your baby with formula.

Dr. David Warmflash is a science communicator and physician with a background in space research and space medicine. He has completed research studies at the NASA Johnson Space Center, the University of Pennsylvania, and Brandeis University. Since 2002, he has collaborated with the Planetary Society on experiments to help us understand the effects of deep space radiation on life forms, and since 2011 has worked almost full-time in medical writing and scientific journals. His areas of focus include the emergence of new biotechnology and its impact on biology, public health, and society. Leading to the concept of vitamins, the first vitamin to be discovered was thiamine or vitamin B1. High concentrations of thiamine are found in the liver, kidneys, brain, heart and skeletal muscles.

This B-complex vitamin is important for energy production, heart protection, enhancing brain activity and for mood regulation and overall well-being.

Symptoms of vitamin B1 (Thiamine) deficiency include anorexia, muscle pain, muscle atrophy, poor memory, insomnia, irritability, tachycardia, hypotension, chest pain, dysphagia, constipation, fatigue, etc.

The Vitamin B Complex Refers To All Of The Known Essential Water Soluble Vitamins Except For Vitamin C. Each Member Of The B Complex Has A Unique Structure.

Low thiamine nutritional status is associated with reduced food intake and increased energy expenditure, which leads to weight loss. Thiamine deficiency inhibits the action of compounds that regulate food intake and energy metabolism.

Such deficiency affects a part of the brain, which produces hormones connected to hunger and energy balance. Eating foods rich in thiamine can restore appetite and reduce weight caused by thiamine deficiency.

Therefore, it is important to correct thiamine levels to improve the overall health status of such individuals. (1)

Getting enough thiamine from food is essential to support healthy brain function. It energizes the brain and improves memory, learning and thinking processes. It protects the outer layer of nerve cells and prevents their destruction.

Swanson Vitamin B1 (thiamin)

In addition, the human brain needs thiamine to use glucose for energy. Without thiamine, brain cells do not receive energy and they die. This important vitamin is also necessary in the production of brain chemicals that send signals to other cells.

Individuals who lack thiamine are at a higher risk of developing Alzheimer’s disease. Eating enough food sources of thiamine can reverse or prevent cognitive decline and reduce the symptoms of Alzheimer’s disease. (2, 3)

Clinical studies have shown that not getting enough thiamine can increase the risk of heart disease. Thiamine supplementation improves the heart’s ability to pump blood efficiently. It enhances the relaxation and contraction of the heart muscle and thus, it improves the overall heart function.

Deficiency of thiamine makes the energy of the heart scarce and reduces the ability of the heart to work effectively. Moreover, it increases the risk of heart disease and heart failure. (4, 5)

Can Vitamin Deficiency Cause Anxiety?

The human brain is sensitive to thiamine deficiency. Literature has found that low concentrations of thiamine are associated with depression and anxiety.

Thiamine is needed for the production of brain chemicals that fight depression, stimulate mood, improve social behavior and reduce depression symptoms. In addition, thiamine protects brain cells from oxidative stress, which otherwise leads to a decrease in the population of brain cells.

Thiamine deficiency increases the risk of brain damage, which causes behavioral changes. Such damage can be prevented by getting enough thiamine through food and supplements. (6)

Pain, tenderness, weakness and muscle stiffness associated with inflammation have a negative impact on overall quality of life. This condition can arise from thiamine deficiency.

Can A B Complex Supplement Improve Your Overall Wellbeing?

Correcting the nutritional status of thiamine improves energy metabolism and reduces muscle fatigue. Making food sources rich in thiamine a part of the daily diet can be beneficial for individuals with muscle pain and weakness. (7)

Low levels of thiamine in the body can affect the sleep cycle and lead to insomnia. Thiamine is involved in the synthesis of neurotransmitters that play an important role in the regulation of sleep and the circadian cycle.

Moreover, thiamine is required for the production of sleep chemicals that promote sleep. For this reason, thiamine deficiency disrupts sleep and causes insomnia. (8) DON’T MISS × Free Protein Box with $75+ Order! | No code required. Ends 10/31 | Exemption applies.

You may be surprised to know that there are 8 vitamins that make up the B vitamin group. In this article, we will consider about vitamin B1. You may know vitamin B1 by its other name, thiamin.

Thiamine May Relieve Fatigue In Hashimoto’s Patients

Vitamin B1 is

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