White Blood Cells In Urine No Bacteria – Urinalysis is part of routine prenatal care and is used to diagnose any health conditions during pregnancy, including kidney infections, preeclampsia, and XA pregnancy disease, which is characterized by high blood pressure, water retention, and protein levels in the urine. and gestational diabetes i XA, a condition characterized by elevated blood sugar levels due to hormonal and body changes during pregnancy. . It can also detect an increase in white blood cells in urine during pregnancy, which may indicate the presence of any infection or inflammation in the genitourinary system or urinary tract. You may also need a urine test to check the function of your maternal organs (1) (2).

Read on to learn about the causes, risk factors, symptoms, diagnosis, treatment management, and prevention of white blood cells, or white blood cells (WBC), in the urine during pregnancy.

White Blood Cells In Urine No Bacteria

White blood cells, or white blood cells, are part of the immune system and include granulocytes (neutrophils, eosinophils, and basophils), monocytes, and lymphocytes (T cells and B cells). Together, these white blood cells help the body fight infections and other diseases.

Wbcs (white Blood Cells ) In Urine

Generally, the white blood cell count is measured as part of a complete blood count (CBC) test (3). However, if a urinary tract infection (UTI) or inflammation is suspected during a routine prenatal visit, your healthcare provider may recommend a urine test to detect the presence of white blood cells, specifically neutrophils. Typically, urine is sterile and therefore the normal range of leukocytes in urine is low, i.e., a maximum of 5 leukocytes per high-power field (WBC/HPF) (4).

Dr. Alan Lindemann, obstetrician and former clinical associate professor at the University of North Dakota, Grand Forks, said, “

White blood cells in the blood and urine are elevated during pregnancy, but normal values ​​depend on when you start. If your WBC was 5,000 when you were not pregnant, a WBC of 10,000 or 11,000 while pregnant might be normal, but if you start the pregnancy with a higher WBC, it might go up to 15,000 which is normal

White blood cells in the urine may not mean a bladder infection, but it can be a sign of trouble. Elevated white blood cells may represent a Group B Streptococcus infection, so a urine culture is needed because Group B Streptococcus bladder infection can lead to kidney infection and premature or preterm labor.

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X, also called urinary retention, is a blockage in the flow of urine through the bladder or urethra. . Furthermore, most immunologic changes in the urinary tract peak during this phase (8).

Symptoms of white blood cells or leukocytes in a pregnant woman’s urine sample may vary depending on the underlying cause. Some of these symptoms include (13) (14)

There are two ways to check your urine for white blood cells during pregnancy: a clean urine sample or a sterile catheter. Because leucorrhea increases during pregnancy, sterile catheterization is the most accurate test for white blood cells during pregnancy

Leukocyte esterase test results may be affected by how the urine sample is stored. Positive samples have the potential to become negative after 24 h of storage (19).

My Urine Culture Is Negative, Can I Still Have A Bladder Infection?

Urine sediments from fresh urine samples were centrifuged at 1,500 to 3,000 rpm for 5 minutes and resuspended in the remaining liquid for analysis. Deposit a drop onto a clean glass slide, cover with a coverslip, and observe under a microscope.

X An automated screening device that analyzes urine to diagnose urinary tract infections (UTIs). . Therefore, urine samples from pregnant women may sometimes test positive for leukocytes (20).

Treatment options may vary depending on the cause and level of elevated white blood cells in the urine. Your prenatal care regimen may include some standard treatments to help balance or reduce the levels of white blood cells in your urine during pregnancy:

Treatment should be initiated immediately after detection of high levels of leukocytes in a urine sample to prevent adverse obstetric outcomes. Some maternal complications include (10)

Proteinuria: Causes, Symptoms, Tests & Treatment

Here are some tips that may help prevent elevated white blood cells in urine and improve maternal health (13) (18):

Yes. Normally, your urine may contain 0–5 WBC/HPF, even during pregnancy. However, if the WBC/HPF level exceeds 5, it may be a sign of urinary tract infection or inflammation, which may require treatment (4).

Yes. In addition to urinary tract infections, leukocytosis in pregnant women’s urine may be due to cystitis, pyelonephritis, or various genital infections, which can increase the risk of fatal complications for the fetus. However, fetal death in this setting is rare (10).

Too many white blood cells in the urine for an extended period of time may indicate a serious underlying infection. Severe infections may also cause other symptoms. Therefore, timely treatment is crucial to avoid adverse effects on maternal and infant health.

What Is Bacteria? Good Vs. Bad, Benefits, And Common Types

High levels of white blood cells in the urine during pregnancy can be caused by different infections caused by bacteria or fungi. Symptoms of high white blood cell levels depend on the underlying cause, but may include frequent urination, fever, and nausea. This condition is usually discovered during a routine urine test during pregnancy, and depending on the cause and severity, you may be prescribed antibiotics or home remedies. Therefore, with timely and effective medical intervention, the condition can be controlled. However, delaying treatment may cause an extreme increase in white blood cells, leading to complications.

An increase in white blood cells in the urine during pregnancy indicates an underlying infection. Recognizing early symptoms and underlying causes is critical for appropriate management. Let’s take a look at the infographic below which explains various possible symptoms and causes of elevated urinary white blood cells during pregnancy.

Revealing potential causes of high levels of white blood cells in urine during pregnancy and when to talk to your doctor

The articles are written after analyzing the research works of expert authors and institutions. Our references include resources established by authorities in their fields. You can learn more about the authenticity of the information we provide in our editorial policy.

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Dr. Esha Chainani is an obstetrician, gynecologist and laparoscopic surgeon in Mumbai. She has over four decades of experience specializing in pregnancy care, high-risk pregnancies, fertility, vaginal bleeding, uterine fibroid surgery, fertility surgery, PCOS, and endometriosis. Dr. Chainani has authored several internationally published research papers and health articles. She is the founder of Premaa, a company dedicated to reducing maternal… more

Reshmi Das has over four years of experience as a clinical coordinator, medical content writer, and medical conference coordinator. Her continued interest in medical journals and writing has led her to write deeply researched articles for . She writes about health and wellness articles for children, pregnant and breastfeeding women. Reshmi has completed her postgraduate graduation in Biotechnology from MITS Institute of Biotechnology,…more

Rebecca is a pregnancy writer and editor with a passion for providing engaging, research-based content in the areas of fertility, pregnancy, birth and postpartum. She graduated in Biotechnology and Genetics from Loyola College, Osmania University, and received certification in “Nutrition and Lifestyle during Pregnancy” from Ludwig Maximilian University Munich (LMU). She has always been dedicated to health and…more

Aneesha holds a Bachelor’s degree in Biotechnology from USTM, Meghalaya and a Master’s degree in Applied Microbiology from VIT, Vellore. With two years of experience, she has worked on different research projects in the field of food science. Additionally, she has an internship experience with Indian Oil Corporation Limited as an R&D project intern. As a contributor to , Aneesha ensures… More Morphology: The size of normal red blood cells is 6-9 microns. They are round and biconcave. In hypertonic urine, the cells have a zigzag shape; are shrunk and have small spikes. In hypotonic urine, the cells are enlarged and colorless. Malformed red blood cells may be caused by glomerular disease and may appear misshapen, fragmented, and/or have bulges. “Ghost cells” is a term used to describe red blood cells that lyse leaving behind an outer membrane.

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Disease Relevance and Clinical Significance: Pathological causes of red blood cells in urine include glomerular mesangial injury/disease, urinary tract infection, nephrolithiasis, and kidney injury. Non-pathological causes of red blood cells are usually due to menstrual contamination.

Helpful tip: Red blood cells, yeast and oil droplets look similar and need to be distinguished. To differentiate between red blood cells and yeast, acetic acid (1:1) can be added to the urine sediment. Red blood cells will lyse in the presence of acetic acid, but the yeast will remain intact. To differentiate between red blood cells and oil droplets, use a lipid stain such as Oil Red O or Sudan III.

Morphology: White blood cells are 10-14 microns in size. The most common white blood cells in urine are neutrophils. Therefore, most white blood cells in the urine will be granular, with the exception of lymphocytes and monocytes.

Disease Relevance and Clinical Significance: Pathological causes of leukocytes in urine include urinary tract infection, inflammation, and glomerular disease. The presence of eosinophils in urine is associated with interstitial nephritis.

Solution: Pus Cells In The Urine

Helpful tip: When distinguishing between white blood cells and red blood cells, white blood cells appear more fine-grained and “fuzzy” compared to red blood cells. Also note the size difference, white blood cells are generally larger than red blood cells.

Morphology: Squamous cells are the largest cells, measuring 50-100 microns. The cell is irregular in shape and consists of a nucleus the size of a large red blood cell. The edges of the cell membrane are often folded, irregular, or wrinkled. Squamous epithelial cells originate from the outer mucosa of the lower urinary tract and genitals.

Helpful tip: When squamous cells fold, they may look something like

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