Where Is The Spleen On Your Body – The spleen is located under the rib cage. Removes unhealthy, old and malformed red blood cells from circulation.Nerthuz/iStock/Thinkstock

The spleen helps keep harmful microorganisms out of the bloodstream. Contains key components of the body’s immune system. The spleen also removes unhealthy, old and misshapen red blood cells from the circulation.

Where Is The Spleen On Your Body

Where Is The Spleen On Your Body

Red blood cells carry oxygen around the body and remove carbon dioxide (a waste product). These disc-shaped cells are filtered by the spleen based on their physical characteristics. They can only re-enter the bloodstream if they can pass through a tiny structure in the spleen called the interendothelial gap. When red blood cells change in size, shape, or ability to deform, they cannot pass through.

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Under certain conditions, such as hereditary spherocytosis, malformed red blood cells can become trapped in the spleen, causing anemia. In addition, certain diseases such as malaria, leukemia and lymphomas can cause the spleen to enlarge and lead to it filtering out not only abnormal cells but also healthy red blood cells.

Studying how the human spleen filters defective red blood cells has been challenging. The anatomy and physiology of the human spleen differs from conventional laboratory animal models. Invasive procedures such as biopsy or needle aspiration can cause dangerous bleeding. A group of researchers led by dr. Subra Suresh at Carnegie Mellon University and Dr. Ming Dao at MIT, tackled the problem using computer simulation tools. Their work was partially funded by the National Heart, Lung, and Blood Institute (NHLBI). The study was published online in

The team developed computer simulations of the mechanics of red blood cells as they pass through the spleen. The researchers found that the cells were severely deformed when they crossed the narrow splenic gap. They found that this contrasted with the simple spherical deformation that occurs in narrow blood capillaries.

The analyzes showed the limits of surface area and volume within which red blood cells can cross the spleen. The work showed how the splenic cleft determines the size and shape distribution of healthy red blood cells. The team’s predictions were consistent with independent experimental results using healthy, engineered and infected human red blood cells.

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“Computational and analytical models from this work, together with various experimental observations, point to a more detailed picture of how the physiology of the human spleen likely affects several key geometric features of red blood cells,” says Suresh.

“We presented results showing that the spleen is the main organ that determines the shape of circulating red blood cells,” adds Dao.

This work may lead to a better understanding of the role of the spleen in various diseases. The findings could have implications for future therapeutic approaches.

Where Is The Spleen On Your Body

References: Biomechanics of red blood cells in the human spleen and implications for physiology and disease. Pivkin IV, Peng Z, Karniadakis GE, Buffet PA, Dao M, Suresh S.

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Funding: National Heart, Lung, and Blood Institute (NHLBI); National Science Foundation; US Department of Energy; Swiss Platform for Advanced Scientific Computing; and the Singapore-MIT Alliance for Research and Technology.

Research Matters is a weekly update of peer-reviewed research highlights. It was published by the Office of Communications and Public Relations in the Office of the Director. A padlock (lock icon Locked lock) or https:// means that you have connected securely to the .gov website. Only share sensitive information on official, secure websites.

Your spleen is an organ above your stomach and below your ribs on the left side. It’s about the size of your fist. The spleen is part of your lymphatic system, which fights infection and keeps body fluids in balance. It contains white blood cells that fight germs. Your spleen also helps control the amount of blood in your body and destroys old and damaged cells.

Certain diseases can cause the spleen to swell. An injury can also damage or rupture the spleen, especially if it is already swollen. If your spleen is too damaged, you may need surgery to remove it. You can live without a spleen. Other organs, such as your liver, will take over some of the spleen’s work. Without a spleen, however, your body will lose some of its ability to fight infection.

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The information on this website should not be used as a substitute for professional medical care or advice. If you have questions about your health, contact a healthcare professional. The spleen is an organ located under the rib cage on the upper left side of the abdomen. It helps fight infection and filters unnecessary material, such as old or damaged blood cells, from the blood.

Figure 1. Illustration of the spleen with blood vessels, including the splenic artery (red) and splenic vein (blue).

Where Is The Spleen On Your Body

A splenectomy is a surgical procedure to remove the spleen. The most common reason for a splenectomy is to treat a ruptured spleen, which is often the result of an abdominal injury. A splenectomy may be used to treat other conditions, including an enlarged spleen that causes discomfort (splenomegaly), certain blood disorders, certain cancers, infections, and noncancerous cysts or tumors.

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Splenectomy is most often performed laparoscopically through 3 small incisions. With this type of surgery, you may be able to leave the hospital the day after surgery and make a full recovery within two weeks.

After a splenectomy, other organs in the body take over most of the functions previously performed by the spleen. You can be active without a spleen, but you are at greater risk of getting sick or getting serious infections. This risk is greatest shortly after surgery.

To reduce the risk of infection, you should receive certain vaccinations to prevent certain infections. These include vaccinations against Haemophilus influenzae type B, Streptococcus pneumoniae and Neisseria meningitidis. Ideally, these vaccinations should be given at least 2 weeks before surgery. Your spleen is an organ in the upper left part of your abdomen below your breastbone. The main jobs of your spleen are to filter old and damaged red blood cells from your blood and to produce lymphocytes (special white blood cells) that fight infection.

If you have a blood problem, you may be given medication to treat or manage the problem.

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Your surgeon will separate your spleen from the surrounding organs. Metal clips will cut off the blood supply to the spleen. Your surgeon will place a bag around your spleen and remove it.

Your surgeon will make a small incision on or near the belly button. They will make several small cuts in your abdomen so that tubes (ports) can be inserted into your abdomen. Your surgeon will insert surgical instruments through the door along with a telescope to see inside your abdomen and perform the operation.

The operation is the same, except that it is performed through a larger incision in the upper abdomen or under the breastbone.

Where Is The Spleen On Your Body

If you smoke, quitting now can reduce your risk of developing complications and improve your long-term health.

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Try to maintain a healthy weight. If you are overweight, there is a higher risk of developing complications.

Regular exercise should help you prepare for surgery, help you recover, and improve your long-term health. Before starting exercise, consult a medical staff or personal physician for advice.

If you have not received the coronavirus (COVID-19) vaccine, you may be at increased risk of serious illness related to COVID-19 during your recovery. Ask your doctor or health care provider if you want to receive the vaccine.

You should go home after 1 to 2 days if you had keyhole surgery, or 5 to 7 days if you had open surgery.

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You should be back to work in 3 to 4 weeks, depending on how much surgery you need and the type of work you do.

Regular exercise should help you get back to your normal activities as quickly as possible. Before starting exercise, consult a medical staff or personal physician for advice.

Elective splenectomy is usually recommended for certain blood problems and to eliminate the life-threatening risk of splenic rupture.

Where Is The Spleen On Your Body

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Anatomical Structure Of The Abdominal Organs. Spleen, Liver, Gallbladder, Stomach, Intestines, Colon, Pancreas. Vector Illustration Stock Vector Image & Art

Spleen – a channel for better health Surgical removal of a diseased or damaged spleen is possible without causing serious harm to the person. Read more on the Better Health Channel website Splenomegaly – Better Health Channel Any condition that causes blood cells to break down rapidly can put a lot of strain on the spleen and make it enlarged. Read more on the Better Health Channel website Heart murmurs – Better Health Channel Many children have innocent heart murmurs that do not require treatment, but often require medical examinations

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