Where In Your Body Is Your Spleen – The liver is located under the rib cage. Removes unhealthy, old, and dysfunctional red blood cells from circulation.Nerthuz/iStock/Thinkstock

The liver helps keep harmful bacteria out of the blood. It contains important components of the body’s immune system. The liver also removes unhealthy, old, and damaged red blood cells.

Where In Your Body Is Your Spleen

Red blood cells carry oxygen throughout the body and remove carbon dioxide (a waste product). These disc-shaped cells are filtered in the spleen according to their physiological characteristics. They can only re-enter the bloodstream if they are able to cross a small splenic structure called the ‘interendothelial slit’. When the size, shape, or capacity of red blood cells in the blood is changed, they cannot pass.

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In certain cases, such as hereditary spherocytosis, the wrong red blood cells can get stuck in the spleen, causing anemia. In addition, some diseases – such as malaria, leukemia, and lymphomas – can cause the spleen to enlarge and lead to filtering out not only abnormal cells but also healthy red blood cells.

Learning how the human spleen filters defective red blood cells has been a challenge. The anatomy and physiology of the human pancreas differs from that of normal laboratory animal models. And invasive procedures, such as biopsy or needle aspiration, can cause serious bleeding. A group of researchers led by Dr. Subra Suresh of Carnegie Mellon University and Dr. Ming Dao of MIT approached the problem using computational simulation tools. Their work was partially funded by the National Heart, Lung, and Blood Institute (NHLBI). The study was published online

The team produced mathematical simulations of the mechanics of red blood cells as they pass through the spleen. The researchers determined that the cells were significantly distorted as they passed through the narrow splenic slits. This is in contrast, they found, to the simple change in lead pattern that occurs in narrowed blood vessels.

The analysis revealed the limits of the area and volume that red blood cells can pass through the spleen. The work showed how the splenic membrane determines the size and distribution pattern of healthy red blood cells. The team’s predictions are consistent with results from independent experiments using clinically, artificially modified, and infected human red blood cells.

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“The computational and analytical methods of this work, together with various experimental observations, indicate a detailed picture of how the physiology of the human pancreas is likely to be influenced by several important geometric features of red blood cells,” Suresh said.

“We have presented results that show that the spleen is the main organ that defines the pattern of red blood cell circulation,” Dao added.

This work may lead to a better understanding of the role of the pancreas in various diseases. The results may have implications for future therapeutic approaches.

References: Biomechanics of red blood cells in the human spleen and physiological and pathological consequences. Pivkin IV, Peng Z, Karniadakis GE, Buffet PA, Dao M, Suresh S.

Splenomegaly: What Is It, Causes, Severity, Diagnosis, Treatment, And More

Funding: National Heart, Lung, and Blood Institute (NHLBI); National Science Foundation; US Department of Energy; Swiss Platform for Advanced Scientific Computing; and the Singapore-MIT Alliance for Research and Technology.

Research Matters is a weekly update of research highlights reviewed by experts. Published by the Office of Communications and Public Relations in the Office of the Director. Your liver is an organ located on the upper left side of your abdomen below your ribs. Your spleen’s main job is to filter your blood from old and damaged red blood cells, and to produce lymphocytes (special white blood cells) that fight infections.

If you have a problem with your blood, you may be able to get medication to treat or manage the problem.

Your surgeon will separate your spleen from the surrounding organs. They will close the blood supply to your spleen using a clamp. The surgeon will place a bag around your spleen and remove it.

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The surgeon will make a small cut in or near your belly button. They will make several cuts in your stomach so that the tubes (ports) can go into your stomach. The surgeon will insert surgical instruments into the ports along with a telescope to see inside your abdomen and perform surgery.

The surgery is the same but is done through a large incision in your upper abdomen or under your ribs.

If you smoke, quitting now can reduce your risk of complications and improve your long-term health.

Try to maintain a healthy weight. You are at a higher risk of complications if you are overweight.

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Regular exercise should help you prepare for surgery, help you recover and improve your long-term health. Before you start exercising, ask your healthcare team or GP for advice.

If you don’t get the coronavirus (COVID-19) vaccine, you may be at increased risk of serious illness related to COVID-19 while you recover. Talk to your doctor or health care team if you would like to be vaccinated.

You should be able to go home after 1 to 2 days if you had keyhole surgery or after 5 to 7 days if you had open surgery.

You should be back at work 3 to 4 weeks later, depending on how much surgery you need and your type of work.

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Regular exercise should help you get back to normal activities as quickly as possible. Before you start exercising, ask your healthcare team or GP for advice.

An elective splenectomy is often recommended for certain problems with your blood and to rule out a life-threatening rupture of your spleen.

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Spleen – A Channel to Better Health Surgical removal of a diseased or damaged spleen is possible without serious harm to the person. Read more on the Good Health Channel Splenomegaly – The Good Health Channel Any condition that causes rapid breakdown of blood cells can put a lot of stress on the spleen and cause it to become enlarged. Read more on the Good Heart Channel – the Good Health Channel Many children have innocent murmurs that don’t require any treatment, but medical tests are often needed to make sure. Read more on the Good Health website Immune thrombocytopenic purpura (ITP) – The Good Health Channel Idiopathic thrombocytopenic purpura (ITP) is a rare autoimmune disease in which a person’s immune system destroys the platelets that help their blood clot. . Read more on the Better Health channel website

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You are welcome to continue browsing this site in your browser. Some features, tools or interactions may not work properly. The spleen filters your blood and also stores red blood cells, platelets, and white blood cells. But if your spleen is removed, other parts of the lymphatic system can take over these functions.

Anatomy Of The Abdominal Viscera: Pancreas And Spleen

The liver is part of your body’s lymphatic system. The lymphatic system helps remove waste from the body, maintain fluid balance, and make and activate infection-fighting white blood cells in the immune system. A

Showed that the spleen is also responsible for making substances that play an important role in inflammation and healing.

The liver sits in the upper left part of your abdomen. It is located behind your ribs, under your diaphragm, and above and behind your abdomen.

Healthy individuals. It can get bigger when a person is sick or injured. Your liver is involved in your body’s immune response, and the recycling of old blood cells.

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The number of red blood cells that carry oxygen throughout your body, and the number of platelets, which are cells that help your blood clot. It does this by breaking down and removing abnormal, old, or damaged cells.

The liver plays an important role in your immune system’s response. When it detects bacteria, viruses, or other germs in your blood, it produces white blood cells, called lymphocytes, to fight the infections they cause.

The liver is located on the upper left side of the abdomen. It can be found near the abdomen and behind the left rib cage.

Many different conditions can cause the spleen to become enlarged, especially diseases that cause the cells to break down too quickly. Excessive destruction of blood cells, for example, can overwork the spleen, causing it to enlarge.

Screening The Spleen

When your spleen gets bigger, it can’t filter your blood as effectively as it once did. Maybe suddenly

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