What Is The Function Of Vitamin D3 – The main function of vitamin D in the body is to help the intestines absorb calcium, but it does more. Vitamin D, calcium levels and Parathyroid function are closely related. To better understand this relationship, we need to discuss in advance how the body produces and activates vitamin D. There are two ways in which the body converts the final chemical into vitamin D: (1) using sunlight (UVB) to convert cholesterol into inactive vitamins. D (cholecalciferol) or (2) or by taking vitamin D2 or vitamin D3 in our diet. Both processes usually work at the same time for each of us.

These forms of vitamin D pass through the liver where they are converted to Calcidiol or 25 hydroxy vitamin D. After leaving the liver, this inactive form of vitamin D travels through the bloodstream to the kidneys. In the kidneys, PTH promotes the activation of vitamin D3 into Calcitriol or 1, 25 dihydroxy vitamin D3.

What Is The Function Of Vitamin D3

Vitamin D3 activated into the bloodstream and throughout the body. In terms of its effect on calcium balance, it has the greatest effect on the absorption of calcium in the small intestine. It also causes the kidneys to absorb more calcium from the urine, the Parathyroid gland produces less PTH, and the bones release less calcium and phosphorus at the same time, helping the cells that make and repair bone to mature. Stronger.

Blood Sugar Support, Elevated C Reactive Protein, And Immune Support

At the cellular level, vitamin D enters the parathyroid cells and stops the production of PTH and also stimulates the production of a protein called p21. The p21 protein prevents the parathyroid gland from replicating and gets important in the way the parathyroid glands grow.

Vitamin D seems to be involved in many processes in the body. The following is a list of potential benefits of vitamin D; I say potential, because not all of this is clearly shown.

Vitamin D deficiency refers to a condition in which an individual does not have enough vitamin D in his or her body. When vitamin D levels are low, intestinal absorption of calcium decreases, leading to a decrease in blood calcium levels. As a result, the parathyroid gland becomes more active and produces more PTH, which causes calcium to leave the bone, thus weakening the bone. Individuals with vitamin D deficiency can face many health problems if this problem is not addressed in the long run.

The American Academy of Pediatrics recommends that children and infants receive at least 400 IU of vitamin D daily from their diet and nutrition. Meanwhile, research shows that adults who take 700 to 800 IU of vitamin D daily are less likely to break bones.

Hyperparathyroidism And Vitamin D

A 25 hydroxy vitamin D blood test is the primary way to diagnose vitamin D deficiency. During this test, the doctor measures the amount of vitamin D in the human body. If an individual’s vitamin D level is less than 20 ng / mL, he or she will be diagnosed with vitamin D deficiency based on the guidelines of the American Medical Institute. Endocrine experts consider lower levels of 30 ng / mL as vitamin D deficiency. If a person finds that he or she is deficient in vitamin D, there is no need to stress. Doctors will work with patients to determine the root cause of vitamin D deficiency and develop a personal treatment plan.

Vitamin D supplements are available in both pill and liquid forms. They can be taken regularly to help individuals deal with vitamin D deficiency.

For individuals with vitamin D deficiency who are considering dietary changes or taking supplements, it is essential to see a doctor first. This ensures that an individual can work with a doctor to determine a safe and effective way to treat his or her vitamin D deficiency.

Vitamin D & Vitamin K2 are free vitamins. While vitamin D is essential for the absorption of calcium from the gut, vitamin K2 has two functions that help direct calcium to the right place:

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Because vitamin D can enter fat cells, we can store extra vitamin D in our bodies that can build up over time. Vitamin D is one of the four vitamins that can accumulate in the body to toxic levels. Other vitamins when added are excreted in the urine (part of the reason urine changes color with the use of vitamin supplements) Unfortunately, this does not happen with vitamin D. Too much vitamin D can lead to toxicity problems. And it can cause the following symptoms:

High levels of vitamin D can also increase a person’s calcium levels. In this case, an individual may experience confusion, dizziness and arrhythmias.

If vitamin D deficiency is present in a person for a long time, PTH levels may increase, causing the bones to release more calcium into the bloodstream, which may be accompanied by a slight increase in calcium levels, or it may be. Not available. This can lead to symptoms of overactive thyroid gland and also loss of bone mass. This is considered a condition of secondary hyperparathyroidism; After vitamin D deficiency. This condition can usually be easily corrected by replacing vitamin D, which will bring PTH levels back to normal.

Vitamin D deficiency is common in modern society, but it is more common in people with primary thyroid disease. Vitamin D deficiency PHPT is usually present in severe forms of PHPT and comes with a high rate of bone loss or osteoporosis. The reason for vitamin D deficiency is generally unclear, some believe it is due to high PTH levels, resulting in the conversion of 25 OH of vitamin D to 1, 25 OH of vitamin D. Most likely other processes occur in The body lowers vitamin D levels as a way to protect the body against high calcium levels. The cause is not clear, but vitamin D deficiency causes many problems and needs to be treated properly.

Vitamin D3 Supplement

Studies have also shown that large adenomas, higher PTH levels, and more severe bone disease are more common in PHPT patients who are at risk for vitamin D deficiency than other vitamin D-deficient individuals. In the absence of vitamin D, the parathyroid gland is not suppressed and can enlarge, PTH production is not inhibited, so the levels are higher (giving more symptoms) and the bones are less protected, leading to more bone loss.

The combination of PHPT and vitamin D deficiency affects other systems as well, including the pancreas and insulin, blood vessels and kidneys, leading to many other complications.

Although some people still feel that vitamin D replacement is dangerous and can cause problems, research has clearly shown that when vitamin D is replaced in a controlled way with the help of doctors and laboratory tests, it can The safest. In addition, vitamin D replacement does not cause an increase in calcium in the blood or urine, while at the same time lowering PTH levels.

In many cases, blood tests may show that vitamin D 25 hydroxy (25 OH Vit D) levels are low, but 1, 25 dihydroxyvitamin D 1, 25 OH Vit D) is normal or increased. It occurs because PTH is actively converting 25 OH Vit D to 1, 25 OH Vit D.

Vitamin D Pregnancy Supplement

Vitamin D replacement in the PHPT setting has been shown to have positive side effects when monitored by your doctor.

Some patients can increase their vitamin D levels by taking daily or weekly doses. And some will find that taking vitamin D supplements makes them feel worse. Probably because of the high PTH, the supplement turns into a high concentration of 1, 25 dihydroxy vitamin D, the active form that causes symptoms of vitamin D poisoning. When taking vitamin D makes you feel worse, you should stop immediately. In both scenarios, thyroid surgery will not only correct for calcium / PTH (PHPT) imbalance, but also vitamin D deficiency.

A: Yes, as long as vitamin D levels are being monitored. If you are taking vitamin D, you feel worse or have recent discomfort, you should stop immediately and have your blood pressure checked.

A: Stop taking the pill immediately and contact your doctor. It is important to have a blood test at that time to check for calcium, PTH, 25 OH, vitamin D and 1, 25 OH, vitamin D to see if you have vitamin D toxicity and any effects on your parathyroid function. You.

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Answer: The answer is not clear. No one dares enough to do research on people with PHPT and give them extra calcium supplements.

Dr. Babak Larian of CENTER for Advanced Parathyroid Surgery is a head and neck surgeon with many years of experience in parathyroid surgery. He performs extensive tests to determine if an individual is experiencing hyperparathyroidism, vitamin D deficiency, or both. Dr. Larian also works closely with patients to help.

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