What Is Biotin Good For In The Human Body – Vitamin B7, also known as biotin, is one of the most essential water-soluble vitamins. This vitamin is known as vitamin H where the letter “H” stands for “Haar und Haut”, which are the German words for “hair and skin”, for a wide range of metabolic processes in the body including enzyme synthesis for several metabolic pathways. Vital is vital. Metabolism of fats and carbohydrates, as well as the synthesis of amino acids, which are essential for protein synthesis.

Primarily, biotin is a coenzyme required for the synthesis of fatty acids, which are molecules found in fats and oils. glucogenesis, i.e. the synthesis of glucose from amino acids and fatty acids; and the synthesis of leucine, an essential amino acid that the human body cannot produce on its own.

What Is Biotin Good For In The Human Body

Biotin is only synthesized by bacteria, molds, yeasts, algae and certain plants. The human body cannot synthesize biotin on its own and must depend on external food sources to supplement the required amount. It is essential to maintain healthy hair, skin and nails. It improves nerve function and aids in the metabolism of nutrients.

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Biotin was discovered in 1931 by the German scientist Paul Gyorgy when he extracted the compound from the liver and named it vitamin H. It is also listed as one of the safest and most effective drugs in the World Health Organization’s list of essential drugs.

Although biotin cannot be absorbed by the hair or skin, it contributes to the health of nails, skin and hair, and is therefore a key feature in many cosmetic products used to improve the quality of skin and hair.

Biotin is essential for hair, skin and nails. Improves skin texture by preventing oxidative damage. It also rejuvenates and moisturizes the skin, reduces various signs of aging such as wrinkles, fine lines, blemishes, dark circles, etc. and makes it clear. When it comes to hair, biotin is essential for strengthening hair from root to tip. It preserves the natural color of the hair and prevents breakage and hair loss. It locks the moisture in the hair strands and prevents the hair from becoming brittle. Daily consumption of foods and supplements containing biotin is also beneficial for nails. It is also very useful in improving nail quality and preventing nail brittleness.

Several types of scientific research have concluded that biotin is important in controlling the secretion of insulin from the beta cells of the pancreas, thereby lowering blood sugar levels in the body and keeping diabetes under control, and therefore for people with type 1 or type 2 diabetes. 2 suffering is useful. Diabetes or diabetic neuropathy

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Vitamin B7 is also essential in improving the cognitive function of the brain. It helps repair brain cells and in turn is used to treat symptoms associated with psychotic conditions such as brain fog, depression, schizophrenia, hallucinations, etc. It also treats biotin-responsive basal ganglia disease and hence promotes healthy functioning of the nervous system.

Biotin is beneficial for people suffering from kidney problems. It also effectively reduces muscle cramps and pain during dialysis. It is also useful for improving vision and treating conditions such as seborrheic dermatitis, cradle cap in children, and autoimmune diseases such as multiple sclerosis in adults. It is also very vital in promoting the health of the baby in pregnant women and even after birth.

Vitamin B7, also known as biotin, in addition to its main function in improving skin, hair and nail health, plays a key role in maintaining the function of various body organs such as eyes, kidneys and even during pregnancy.

B complex vitamins, including B1, B2, B3, B5, B6, B12, as well as folic acid and biotin, reduce chronic inflammation in the system and maintain optimal concentrations of the critical amino acid homocysteine. It helps prevent health complications in blood vessels, retinal damage, and also reduces the risk of age-related macular degeneration (AMD). Therefore, biotin increases eye health and promotes healthy vision in later years.

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Biotin, along with other B complex vitamins, are all water soluble and therefore do not accumulate in the system and cause damage to kidney tissues. They also facilitate optimal metabolism and digestion processes. Thus, ensuring adequate intake of biotin and other B vitamins helps detoxify the body and increase kidney health.

While folic acid is the most important B vitamin for pregnant women, biotin is also essential to ensure proper nutrition for expectant mothers. Because the body breaks down biotin at a faster rate during pregnancy, doctors and medical professionals have proven that pregnant women need at least 30 micrograms (mcg) of biotin per day to prevent birth defects in the developing fetus as well as reduce Avoid fatigue. and depression in pregnant mothers

Like other water-soluble vitamins, biotin is not made in the body and is washed away, so a diet rich in vitamin B7 food options should be used to avoid deficiency syndromes. Therefore, to meet nutritional needs, one must depend on external food sources and supplements. And for our rest, Mother Nature has provided us with abundant amounts of natural food sources full of vitamin B1 that meet our daily needs.

Although very rare, biotin deficiency mostly occurs due to a lack of this essential substance in the daily diet. Regular consumption of egg whites for several months can lead to biotin deficiency due to the avidin content in eggs. Avidin is a protein found in eggs that binds tightly to biotin in the intestines, preventing them from being absorbed into the body or functioning properly.

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Some of the symptoms of biotin deficiency include hair loss, dry brittle nails, scaling, red rashes around the eyes, nose and mouth, dry eyes, dry scaly skin that causes dermatitis, conjunctivitis, tongue pain, nausea, vomiting and It falls and becomes clear. Apart from appetite, other symptoms are related to mental or nervous problems, which include depression, insomnia, hallucinations, lethargy, numbness, and tingling in the arms and legs.

People who suffer from hereditary biotin deficiency have a weak immune system and are more susceptible to bacterial and fungal infections. Pregnant women are at a higher risk of developing biotin deficiency, so they should eat a balanced diet to avoid deficiency syndromes.

Although a very essential substance, it has been found that high doses of biotin through supplements or food sources can have adverse health effects. There are no official recommended daily allowance guidelines for B7. However, several studies suggest that adults should consume 30 mcg of biotin per day. Anything more than that can cause a skin allergy characterized by rashes, redness, and itching. which can lead to anaphylaxis by reaching the chest. Other symptoms of biotin overdose include excessive thirst, urination, insomnia, and an alarming decrease in vitamin B6 and vitamin C. Because it is beneficial for glucose metabolism, people with diabetes should consult their doctor before taking biotin supplements in excess. It can be harmful.

In certain cases, overdosage can also cause eosinophilic pleuropericardial effusion, which occurs when blood and air enter the pleural space around the lungs, resulting in chronic lung infection.

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A highly beneficial nutrient, this water-soluble vitamin is important for many health benefits such as fat metabolism, improving skin and vision, maintaining a healthy nervous system, and managing diabetes. When taken with prior consultation with a doctor, toxic effects can be avoided and its benefits can be reaped. Biotin is a water-soluble vitamin that is generally classified as a B-complex vitamin. After its initial discovery in 1927, it took an additional 40 years of research to clearly identify biotin as a vitamin (1). Biotin is required by all organisms, but it can be synthesized by some species of bacteria, yeast, mold, algae, and some plant species (2).

Biotin acts as a covalently bound cofactor required for the biological activity of five known mammalian biotin-dependent carboxylases (see below). Such non-protein cofactors are called “prosthetic groups” and are common in water-soluble vitamins. Covalent attachment of biotin to apocarboxylase (ie, protein carboxylase without biotin prosthetic group and catalytically inactive) is catalyzed by the enzyme holocarboxylase synthetase (HCS). The term “biotinylation” refers to the covalent addition of biotin to any molecule, including apocarboxylases and histones. HCS catalyzes the post-translational biotinylation of the amino epsilon group of a lysine residue in the active site of each apocarboxylase, converting the inactive apocarboxylase into a fully active holocarboxylase (Figure 1a). Specific lysine residues in the N-terminal tail of certain histones that aid in DNA packaging in eukaryotic nuclei can also be biotinylated (3). Biotinidase is an enzyme that catalyzes the release of biotin from biotinylated histones and from peptide products of holocarboxylase cleavage (Figure 1b).

• Both acetyl coenzyme A (CoA) carboxylase 1 (ACC1) and acetyl-CoA carboxylase 2 (ACC2) catalyze the conversion of acetyl-CoA to malonyl-CoA using bicarbonate and ATP. However, these two enzymes have different roles in metabolism and different intracellular locations. ACC1 is located in the cytosol and malonyl CoA is produced

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