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Dr. Avinash Singh Hematologist • 20 Years Exp. MBBS Bachelor of Medicine and Bachelor of Surgery, MD – Medicine, DM – Clinical Hematology

What Do Low Hemoglobin And Hematocrit Levels Indicate

What Do Low Hemoglobin And Hematocrit Levels Indicate

The hematocrit test is best defined as a blood test that measures the percentage (or count) of red blood cells in your blood. It should be noted that these cells are mainly responsible for transporting oxygen to different parts of your body, so an abnormal amount can be an indication of certain health conditions. This test can also be referred to as a ‘packed-cell volume’ (PCV) test in medical terms.

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A hematocrit, or PCV, test is performed in most cases as an indispensable part of a complete blood count (CBC). By measuring the proportion (or ratio) of healthy red blood cells in your blood via this test, your doctor can more accurately diagnose your condition or monitor your response to any treatment provided to you.

A hematocrit (or the ratio of red blood cells in your blood) that is lower or higher than normal can indicate one or more underlying health conditions, such as:

A hematocrit blood test is a very simple and common blood test. This test is mainly used to measure the amount (or number) of red blood cells in a blood sample. Furthermore, it should be noted that no fasting or other special preparations are necessary before this test.

A PCV (or hematocrit) test is usually performed by a technician or a nurse in a blood laboratory or clinic. ‘Hematocrit’, as already mentioned above, is the percentage (or ratio) of the total blood volume occupied by red blood cells. Red blood cells are simply meant to transport essential nutrients and oxygen to the tissues of the (human) body.

Complete Blood Count (cbc)

A hematocrit or PCV test requires a blood sample, which is usually drawn using a needle from a vein in one of the patient’s arms. The patient may feel some kind of tenderness at the site (or in the vein) where the needle was inserted, but they will be able to resume their normal activities shortly after blood is drawn. That said, it’s important to keep the area where the needle was inserted clean and covered until it’s completely healed so you don’t end up developing an infection.

Your hematocrit test results will be reported as a percentage of the volume of your blood made up of red blood cells. Normal ranges can vary based on race, age, and gender. Aside from these factors, the definition of a ‘normal’ red blood cell percentage can also vary from one medical practitioner or healthcare provider to the next.

Also note: The normal hematocrit range for children 17 years and younger varies according to their gender and exact age.

What Do Low Hemoglobin And Hematocrit Levels Indicate

Your hematocrit test is just one way to get a solution to your health. Therefore, you should never jump to a conclusion without discussing your test results with your doctor, who will consider the symptoms you are experiencing as well as the results of other diagnostic tests before coming up with a solution or ultimate treatment plan.

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Your hematocrit test can be affected by a variety of factors, which in some cases can lead to inaccurate results. This includes:

That said, your doctor will interpret the results of your hematocrit test, taking into account any potentially complicating factors. If your results show conflicting or unexpected information, the doctor may repeat the hematocrit test and perform other blood tests for a more accurate diagnosis of your individual condition.

All in all, the hematocrit (or PCV) test is a very common and simple type of test that is mainly used to examine a person’s blood. This test can be used to help determine if a person has anemia, polycythemia, an iron deficiency, or other similar blood disorders. The hematocrit test is also used to measure the blood volume of a person receiving blood or blood plasma.

Furthermore, we hope that this article has given you the necessary information on the subject of the hematocrit test. If you have any other questions, please do not hesitate to contact us. We are always happy to help you in any way possible!

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If you have a concern or query, you can always consult a specialist and get answers to your questions! Polycythemia (also known as polycythemia) is a laboratory finding in which the hematocrit (the volume of red blood cells in the blood) and/or hemoglobin concentration in the blood is increased. Polycythemia is sometimes called erythrocytosis, and there is significant overlap in the two findings, but the terms are not the same: polycythemia describes any increase in hematocrit and/or hemoglobin, while erythrocytosis is an increase specifically in the number of red blood cells in the blood.

Absolute polycythemia can be due to genetic mutations in the bone marrow (“primary polycythemia”), physiological adaptations to one’s vironmt, medications, and/or other health conditions.

Laboratory studies such as serum erythropoietin levels and genetic testing may be helpful in clarifying the cause of polycythemia if the physical examination and patient history do not reveal a likely cause.

What Do Low Hemoglobin And Hematocrit Levels Indicate

Mild polycythemia on its own is often asymptomatic. Treatment for polycythemia varies, and typically involves treating its underlying cause.

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Treatment of primary polycythemia (see polycythemia vera) may involve phlebotomy, antiplatelet therapy to reduce the risk of blood clots, and additional cytoreductive therapy to reduce the number of red blood cells produced in the bone marrow.

Polycythemia is defined as serum hematocrit (Hct) or hemoglobin (HgB) exceeding normal ranges expected for age and sex, typically Hct > 49% in healthy adults and >48% in women, or HgB >16.5g/dL in m or > 16.0g/dL in woman.

Different diseases or conditions can cause polycythemia in adults. These processes are discussed in more detail in their respective sections below.

Relative polycythemia is not a true increase in the number of red blood cells or hemoglobin in the blood, but rather an increased laboratory finding caused by reduced blood plasma (hypovolemia, cf. dehydration). Relative polycythemia is often caused by loss of body fluids, such as from burns, dehydration and stress.

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A specific type of relative polycythemia is Gaisböck syndrome. In this syndrome, which occurs mainly in obese m, hypertension causes a reduction in plasma volume, which (among other changes) results in a relative increase in red blood cell count.

If relative polycythemia is considered unlikely because the patient has no other signs of hemoconstriction, and has acquired polycythemia without obvious loss of body fluids, the patient probably has absolute or true polycythemia.

Polycythemia in newborns is defined as hematocrit > 65%. Significant polycythemia can be associated with blood hyperviscosity, or thickening of the blood. Causes of neonatal polycythemia include:

What Do Low Hemoglobin And Hematocrit Levels Indicate

The pathophysiology of polycythemia varies depending on its cause. The production of red blood cells (or erythropoiesis) in the body is regulated by erythropoietin, which is a protein produced by the kidneys in response to poor oxygen delivery.

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As a result, more erythropoietin is produced to encourage red blood cell production and increase oxygen carrying capacity. This leads to secondary polycythemia, which may be an appropriate response to hypoxic conditions such as chronic smoking, obstructive sleep apnea, and high altitude.

Furthermore, certain genetic conditions can impair the body’s accurate detection of oxygen levels in the serum, leading to excess erythropoietin production without hypoxia or impaired oxygen delivery to tissues.

Alternatively, certain types of cancers, especially squamous cell carcinoma, and medications such as testosterone use can cause inappropriate erythropoietin production that stimulates red cell production despite adequate oxygen delivery.

Primary polycythemia, on the other hand, is caused by genetic mutations or defects of the red cell progitors within the bone marrow, leading to overgrowth and hyperproliferation of red blood cells, regardless of erythropoietin levels.

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Increased hematocrit and red cell mass with polycythemia increases the viscosity of blood, which leads to impaired blood flow and contributes to an increased risk of clotting (thrombosis).

The first step in evaluating new polycythemia in any individual is to perform a detailed history and physical examination.

Patients should be asked about smoking history, altitude, medication use, personal bleeding and clotting history, symptoms of sleep apnea (snoring, apnea episodes), and any family history of hematologic conditions or polycythemia. A thorough cardiopulmonary examination, including auscultation of the heart and lungs, can help evaluate for cardiac shunting or chronic lung disease. An abdominal exam can evaluate for plumegalemia, which can be seen in polycythemia vera. Examination of figures for erythromelalgia, clubbing or cyanosis may help determine for chronic hypoxia.

What Do Low Hemoglobin And Hematocrit Levels Indicate

Polycythemia is often initially identified on a complete blood count (CBC). The CBC is often repeated to evaluate for persistent polycythemia.

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Primary polycythemia are myeloproliferative diseases that affect red blood cell precursors in the bone marrow. Polycythemia vera (PCV) (also known as polycythemia rubra vera (PRV)) occurs when excess red blood cells are produced as a result of an abnormality of the bone marrow.

Often, excess white blood cells and platelets are also produced. A hallmark of polycythemia vera is an elevated hematocrit, with Hct > 55% in 83% of cases.

A somatic (non-inherited) mutation (V617F) in the JAK2 gene also predisposes to

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