High Red Blood Cell Count Low Hemoglobin – Although a high red blood cell count does not always indicate a health problem, it can also be a symptom of a disease or disorder in some cases.

Red blood cells (RBC), also called erythrocytes, are cells that carry oxygen throughout the body. It is also one of the main components of blood. Having a high red blood cell (RBC) count means that the number of RBCs in the bloodstream is higher than normal.

High Red Blood Cell Count Low Hemoglobin

When you have signs and symptoms of an illness that may involve problems with red blood cell production, a complete blood count (CBC), which includes an RBC count, is usually ordered to help with the diagnosis. A complete blood count is usually part of the pre-surgery workup as well as a routine physical exam.

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A change in the number of RBC also means that there is a change in the level of hemoglobin and hematocrit in the blood. When the RBC count, hemoglobin, and hematocrit are below the defined normal range, the patient is called anemic. On the other hand, when a person has values ​​that exceed the normal limit, he is called polycythemic. Too many RBCs can cause decreased blood flow and related health problems, while too few RBCs can significantly affect the amount of oxygen reaching the tissues.

Health care providers may order a CBC when a patient shows some common signs and symptoms of anemia, such as:

This blood test can also be done regularly to help patients with blood disorders, such as chronic anemia, bleeding problems, and polycythemia, including kidney disease.

People undergoing cancer treatment are also required to have a regular CBC since radiation therapy or chemotherapy tends to reduce the overall production of blood cells in the bone marrow.

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The following reference ranges are only theoretical guidelines and should not be used to interpret test results. There is variation between the reference range and the number reported by each laboratory that performs the test. Please consult your healthcare provider for the interpretation of your test results.

Although a high red blood cell count does not always indicate a health problem, it can also be a symptom of a disease or disorder in some cases. Lifestyle and health factors can also cause an increase in the number of red blood cells. Among them:

This rare blood disease develops when the body produces too many red blood cells (RBC). If there is an overproduction of red blood cells, the blood becomes abnormally thick, making people more prone to developing blood clots. The formation of blood clots can affect the normal flow of blood through the veins and arteries, and cause a heart attack or stroke.

Impaired blood flow also means that the body’s organs are deprived of the oxygen they need to function normally, and can lead to serious health problems, such as angina and heart failure.

Complete Blood Count (cbc)

Polycythemia vera is a chronic blood disease that can be life-threatening if not properly diagnosed and treated. Although there is no cure for the condition, there are treatments that can help manage the disease and its complications. Treatment for PV may also include more than one treatment method to help manage the disease.

The body tries to compensate and increase red blood cell production for any medical condition that may cause low oxygen levels. These conditions include:

Abnormally functioning kidneys due to kidney disease, kidney transplants, and kidney cancer can cause too much production of erythropoietin, which increases the production of red blood cells.

Some medications, such as methyldopa and gentamicin can increase the red blood cell (RBC) count. Methyldopa is a drug used for the treatment of hypertension (high blood pressure) and gentamicin is an antibacterial drug used for the treatment of bacterial infections in the blood. Be sure to inform your doctor about any medications you are taking.

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When a person is dehydrated, the plasma or liquid component of the blood decreases and increases the concentration of red blood cells.

Your health care provider may recommend certain medications or procedures to lower your RBC count, especially if a medical condition is causing the count to be abnormal.

A procedure called phlebotomy can be performed by a healthcare professional regularly until your red blood cell (RBC) levels are close to normal. In this procedure, a needle is inserted into your vein to draw blood into a designated container or bag.

In people with bone marrow disease or polycythemia vera, healthcare providers can prescribe hydroxyurea, which is an anticancer drug that can help slow down the production of red blood cells in the body. Regular doctor appointments are required while taking this medication to monitor and ensure that the red blood cell count does not drop to dangerous levels.

What Is A Healthy Hemoglobin Level?

A high RBC count is usually found when a doctor orders a blood test to help diagnose a patient’s condition. You can ask your doctor and discuss your blood test results. Having a high red blood cell (RBC) count and other abnormal test results are indications that can help your doctor identify the cause of your condition.

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Is a trusted source for patients to find the top doctors in their area. Be visible and accessible with your contact information, certified patient reviews and online appointment booking functionality. Hemoglobin disorders are a group of inherited conditions that affect a person’s red blood cells. Red blood cells take oxygen from the lungs and deliver it to all body tissues. In people with hemoglobin disorders, the number of red blood cells is low, less able to do their job, or both.

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The most common hemoglobin disorders are sickle cell disease and thalassemia. Some versions of the disease-causing gene also protect against malaria—a deadly parasite carried by mosquitoes. Through natural selection, this gene variation has become very common in certain parts of the world.

The Hbb gene codes for the beta-globin protein. Two beta-globin molecules combine with two alpha-globin molecules to form hemoglobin. If there is a problem with the beta-globin protein, the hemoglobin cannot function properly, and the red blood cells cannot do their job as well.

The HBB gene, on chromosome 11, codes for the beta-globin protein. Two beta-globin molecules combine with two alpha-globin molecules to form hemoglobin.

Hemoglobin protein is the main part of red blood cells. It gives the blood its color and allows it to carry oxygen. The red comes from hemes—an iron-containing molecule found in every globin protein. Heme is necessary for hemoglobin to hold oxygen.

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There are many different versions (alleles) of the HBB gene, each coding for a slightly different beta-globin protein. Some HBB alleles can cause genetic disorders. Each type of beta-globin disorder has a unique set of symptoms, which can range from very mild to life-threatening. In all of these disorders, the symptoms of hemoglobin reabsorption work poorly, which prevents red blood cells from doing their job.

Too little protein. Some alleles of the HBB gene produce very little or no beta-globin protein. It causes some forms of beta-thalassemia, a genetic disorder in which people have too few red blood cells.

Altered protein. Some alleles of the HBB gene code for an unusual form of the beta-globin protein. Depending on how the beta-globin protein is modified, this type of allele can cause several genetic disorders.

From the point of view of the protein being made, the two HBB alleles of a person are dominant. The beta-globin protein is made from both alleles, and they combine randomly to make hemoglobin.

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Normally, people with a healthy HBB allele make enough healthy beta-globin protein, and their red blood cells can do their job. Thus, hemoglobin disorders usually follow an autosomal recessive inheritance pattern: two non-working alleles are required to cause the disorder, one from each parent. Sickle cell disease and many forms of beta thalassemia work this way.

However, in some cases, hemoglobin disorders follow an autosomal dominant inheritance pattern: only one non-functional HBB allele is required to cause the disorder. A child can inherit the disorder directly from the affected mother. Oxygen transport disorders and some forms of beta thalassemia work this way.

With some combinations of alleles—such as the oxygen transport allele plus sickle cell, or the sickle cell allele plus beta-thalassemia—the symptoms of the disorder also follow a dominant pattern. The symptoms a person experiences are the result of the combined effects of both alleles.

Each person inherits two copies (or alleles) of the Hbb gene—one from each parent. Our red blood cells make proteins from both alleles and assemble them into hemoglobin. Hemoglobin molecule can include beta-globin from either allele in any combination.

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Stem cells in red bone marrow divide rapidly, giving rise to all types of blood cells. The Hbb gene is turned on in what will become red blood cells. As they mature, they move into the bloodstream.

Almost all beta-globin in the body is found in

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