High Protein And White Blood Cells In Urine – Leukocytes are white blood cells that are essential to the defense of the immune system. Leukocytes in the urine may indicate infection or inflammation of the urinary tract.

The presence of leukocytes in the urine can be a symptom of an infection. Urinary tract infection (UTI) is often responsible for increased levels of leukocytes in the urine

High Protein And White Blood Cells In Urine

High Protein And White Blood Cells In Urine

This article will explain what an excess of white blood cells in the urine means and how to treat a UTI.

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An abnormally high leukocyte count in the urine indicates inflammation or infection along the urinary tract of the bladder or kidneys.

These are shown in a urine test. While women get tested for urinary tract infections at their first prenatal visit during pregnancy, they may need tests at other times during their pregnancy. Other people may need tests based on their health, symptoms or history of recurrent infections.

The doctor can perform a dipstick test, and a chemical strip detects an enzyme called leukocyte esterase, which shows up in the white blood cells, usually associated with an infection. The dipstick test also highlights nitrites, which are a waste product from the breakdown of certain bacteria.

The presence of nitrites in the urine is highly specific for certain bacterial infections. Nitrite does not occur with all types of bacteria.

Photomicrograph Of Urine Deposit Smear From A Patient With Urinary…

The absence of leukocyte esterase in the urine means that the urine does not contain white blood cells, so it does not carry infectious agents.

The doctor or lab technician may also perform a urine culture. This is the growth of bacteria from the urine to identify the cause of the infection.

If the test for leukocyte esterase is positive but nitrites are absent, an infection may still be present.

High Protein And White Blood Cells In Urine

The test is specific for certain bacterial enzymes, which means it can pick up specific bacterial infections more specifically. However, it is not very sensitive, meaning that the test does not pick up all bacterial infections.

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The presence of leukocytes in the urine without nitrites can also lead to a false-positive result indicating a bacterial infection when none are present. The pathologist or technician will perform further tests to confirm the presence of an infection.

This is especially true when there are other causes of urinary tract inflammation. During the process of giving a sample, the genital canal can sometimes pass leukocytes into the urine.

To avoid a false-positive result, people should clean the area around the urethral opening before giving the sample, using cleansing wipes and keeping their lips or foreskin aside.

Take a sample halfway through urination. The initial urine stream can be contaminated with skin bacteria, so taking a sample this way also reduces the risk of a misleading result.

Leukocytes In Urine During Pregnancy: Causes And Treatment

Phagocytes are produced in the bone marrow. Their job is to swallow foreign particles such as bacteria or parasites. This means surrounding, absorbing and destroying a particle.

Lymphocytes are white blood cells that recognize foreign particles based on previous encounters. They contribute to “adaptive” immunity, the complex ability of the immune system to remember and produce tailored and effective responses to an infection.

Lymphocytes produce antibodies. These bind to foreign particles and allow the immune system to remember them later if the same infection occurs.

High Protein And White Blood Cells In Urine

A doctor often performs a urinalysis during pregnancy to check for leukocytes. This is the test that confirms a bladder or kidney infection.

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This also checks for certain conditions associated with pregnancy. One of these is high blood pressure during pregnancy or preeclampsia. Protein in the urine and elevated blood pressure indicate preeclampsia.

UTIs are common during pregnancy, and doctors often find leukocytes in the urine, suggesting an infection. However, pregnant women can have a bacterial infection in the urine without symptoms.

Most UTIs cause manageable infections that a person can treat with antibiotics. A doctor may prescribe a range of different antibiotics, but certain antibiotics are only prescribed to women when they are pregnant.

More severe or serious infections with complications such as an abscess, kidney involvement, or infection during pregnancy may require more intensive treatment, including hospitalization.

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After identifying the bacteria, the doctor may want to change the course of antibiotics. Certain bacteria can only be treated with specific antibiotics. White blood cells (WBCs) are also called leukocytes. They protect the body from infections by fighting foreign invaders such as viruses, bacteria, fungi or parasites. Phagocytes and lymphocytes are a form of white blood cells (WBCs).

Phagocytes engulf foreign particles such as bacteria. Lymphocytes recognize foreign particles based on previous encounters. Lymphocytes make up our body’s adaptive immunity. They also produce antibodies that bind to foreign particles so they can be identified for destruction.

Because leukocytes help fight diseases and infections, high levels of leukocytes in the urine indicate an infection or inflammation of the bladder or kidneys. It means the body is trying to fight a urinary tract infection. It can also indicate damage to the urethra, bladder and urethra.

High Protein And White Blood Cells In Urine

It can also indicate kidney stones. A high number of leukocytes in the urine can also indicate high blood pressure, diabetes or other kidney diseases. A persistently high leukocyte count in the urine can adversely affect the kidneys or bladder. Excess leukocytes that are killed or damaged while fighting an infection are excreted from the body through urination.

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For this reason, the presence of leukocytes in the urine does not always mean an infection. The normal range of leukocytes in urine is 0-5 WBC/HPF. The size of the urinary tract in women is smaller compared to that of men and therefore more leukocytes are found in the urine of women than in men. Pregnant women also tend to show leukocytes in the urine.

During pregnancy, the leukocyte count may suddenly increase in the urine. One reason may be vaginal contamination. Other causes are increased levels of protein excreted in the urine and bladder infection. If leukocytes are frequently reported during a routine urinalysis, it is advisable to consult a gynecologist.

Kidney problems can cause an increase in the number of leukocytes in the urine. The infection starts in the urinary tract and spreads to the kidneys. Such an infection is called pyelonephritis, and it can affect any part of the kidney system. It can affect the bladder, urethra and urethra. People with weakened immune systems and people who use urinary catheters are at increased risk of developing pyelonephritis.

Kidney stones are also proven to be dangerous because they contain calcium salts that can block the urinary tract. Obstructions can lead to a bacterial infection and the presence of leukocytes in the urine.

What Do Leukocytes In Urine Mean?

Having sex allows bacteria to migrate into the urinary tract, which increases the leukocyte count in the urine.

In many cases, when the bladder is full, there is an urge to urinate to empty the bladder. In some cases, the urine left in the bladder acts as a good medium for bacteria to grow when the urine is not completely voided or when voiding is delayed. This then leads to bacterial infection of the bladder and an increase in the number of leukocytes in the urine.

The most common causes of urinary tract obstruction are kidney stones, prostatic hypertrophy, and pelvic trauma. Due to this blockage, the urinary system is damaged, which leads to the appearance of leukocytes in the urine. In some cases, blood can also be seen in the urine.

High Protein And White Blood Cells In Urine

Interstitial cystitis is also known as bladder pain syndrome. It causes pressure and pain in the bladder, and excessive urination can cause urinary tract infections and increase the leukocyte count in the urine.

Summary Urine Normal Values, Their Significance

1) Fewer UTI symptoms – The most common symptoms include dysuria or acute pain, frequent urination, urgency and incontinence. There may also be hematuria or blood in the urine and foul-smelling or cloudy urine.

2) Upper UTI Symptoms – Apart from the above symptoms, patients may also show symptoms like suprapubic pain, fever, chills, nausea, vomiting and costovertebral angle sensitivity (CVAT).

A urine sample is usually tested for white blood cells or leukocytes, red blood cells (RBCs), bacteria, and other substances. When the urine is positive for bacteria, a urine culture is performed to identify the type of bacterial infection.

This is the first step in diagnosing urinary tract infections (UTIs). A microscopic examination is done for pyuria (pus in the urine) and hematuria (blood in the urine). Pyuria is common in most women with UTIs, and in some, cystitis. Midstream clean urine is tested to assess for pyuria.

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Urinalysis is the most accurate way to detect bacteremia (bacteria in the urine) in symptomatic women. The presence of bacteria in the urine is not considered a sole criterion for the diagnosis of UTI. The three acceptable methods for urine collection are midstream clean capture, catheterization, and suprapersonal aspiration.

Ten or more leukocytes per cubic milliliter of urine are considered abnormal. Women with UTIs have higher than normal leukocyte counts per cubic milliliter. In centrifuged specimens, more than 8-10 WBC/HPF indicates infection.

If at least one bacterium is present in an oil immersion field from a clean catch and uncentrifuged urine specimen, it is indicated.

High Protein And White Blood Cells In Urine

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