Diseases That Cause High White Blood Cell Count – During pregnancy, your blood volume increases by up to 50%. Decreased hemoglobin level and hematocrit i X percentage of red blood cells (RBC) in the blood (especially in the last trimester), platelet count is also slightly decreased. However, after pregnancy there is an increase in white blood cells (WBCs) in the blood, called leukocytosis.

Leukocytes or WBCs are classified as agranulocytes (lymphocytes and monocytes) and granulocytes (eosinophils, neutrophils and basophils), which form the body’s immune system and fight infection (1).

Diseases That Cause High White Blood Cell Count

Read this post to learn about the causes of high WBC count in pregnancy and the complications associated with this condition.

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After pregnancy, the normal WBC count (leukocytosis) gradually increases, with little change towards an increased percentage of neutrophils.

Leukocytosis begins in the first trimester, continues throughout pregnancy, peaks at delivery, and usually normalizes after four weeks (1) (2).

XA is a pregnancy condition characterized by hypertension, protein in the urine, and water retention and the onset of gestational diabetes mellitus

(GDM) (3) (4). Therefore, leukocyte counts must be accurately interpreted and correlated during your prenatal visit and postpartum care (1).

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During pregnancy, white blood cells are often checked to look for signs of infection or inflammation in the body. WBC levels increase during gestation from eight to forty weeks. As seen in the graph below, they peak at week 32 and begin to slope downward (12).

Even in a healthy pregnancy, it is normal for a woman’s WBC count to increase, especially in late pregnancy. However, if this elevation is accompanied by any signs of infection or other medical conditions, it will likely warrant further testing and evaluation.

Specific causes of an elevated WBC count include bacterial or viral infections, leukemia, rheumatoid arthritis, tuberculosis, certain medications (such as epinephrine

XA hormone as well as a neurotransmitter responsible for the body’s fight or flight response or corticosteroids), severe allergic reactions and even severe stress. Any bacterial or viral infection in the body can cause an increase in a person’s white blood cell count.”

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However, due to the physiological stress caused by pregnancy, your WBC count may be high even in a normal pregnancy. Therefore, maternal WBC count cannot be an early screening technique to detect serious pregnancy complications (5). Conversely, an increase in the WBC count in your urine sample indicates a urinary tract infection (UTI) (6).

Recalling events during a visit to the emergency room during pregnancy (due to suspected blood in the urine), a mother of twin girls said, “The doctor came to tell me about my elevated WBC (white blood cell) count and yes, indeed, blood in my urine. I ended up being diagnosed with a small bladder infection, causing my urine to bleed. Prego-friendly antibiotics will do the trick to clear it up (i).

XA is a complex system of glands and organs that produce hormones, metabolic processes, and various changes in the reproductive system that nourish the developing fetus and prepare the body for labor and delivery. As your pregnancy progresses, this physiological and psychological stress increases your leukocyte count because the leukocytes receive stimulatory impulses (7).

In a healthy pregnancy, leukocytosis is usually referred to as an increased percentage of neutrophils in the blood. However, there are many types of WBCs and high levels of other WBCs may be indicative of various diagnoses (1) (8).

White Blood Cell

An increase in WBC count is mainly due to an increase in neutrophil and lymphocyte numbers (1).

Studies have shown that lymphocyte counts decrease during the first and second trimesters and increase during the third trimester (1).

Routine blood tests during pregnancy, such as a complete blood count (CBC) test, usually measure the leukocyte count. Your doctor may run diagnostic tests for hemoglobin, WBC, and platelet count at almost every prenatal care visit to look for conditions that may complicate pregnancy (6).

An elevated white blood cell count may not indicate any symptoms during pregnancy. However, symptoms of a high WBC count in non-pregnant individuals usually include (9)

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If you notice any of these symptoms while pregnant, contact your healthcare provider, as it could be a sign of an infection or underlying medical complication.

Although leukocytosis is common in pregnancy, it can also result from an underlying problem that simple WBC count tests cannot detect, necessitating additional screening. In the first trimester, higher platelet levels and WBC counts are associated with a higher risk of miscarriage, thus highlighting the importance of monitoring these markers for possible pregnancy complications (5) (10).

A high WBC count during pregnancy, also known as leukocytosis, is induced by the physiological stress of pregnancy. Moderate increase in WBC count is normal during pregnancy. However, if the WBC count is abnormally elevated, it may indicate an underlying condition or infection (8).

Regular blood tests administered by health care providers throughout pregnancy help monitor any potential abnormalities and ensure the well-being of both mother and baby. However, you can take simple precautions to reduce your risk of infection and inflammatory conditions, such as maintaining good hygiene, staying hydrated, eating a balanced diet, and following religiously prescribed medications (13).

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Although there are no characteristic symptoms to depict a high WBC count during pregnancy, some women may experience bleeding easily, high fever, fatigue and weight loss. Also, during pregnancy, the white blood cell (WBC) count may increase starting as early as the first trimester. This is due to the sudden pregnancy related changes that occur in the body. Although a slight increase in WBC count may be expected during pregnancy, it can sometimes be a sign of infection, dehydration, or other medical problems. Therefore, it is ideal to seek medical advice if you experience any unusual symptoms while pregnant to prevent complications that may affect maternal health.

One of the hematological parameters during pregnancy is an elevated white blood cell (WBC) count (leukocytosis), which is usually normal. However, some underlying problems can increase the WBC count during pregnancy. The infographic below covers various white blood cell growth effects during pregnancy

Learn about the symptoms of an elevated white blood cell (WBC) count and effective management strategies. Get the answers you need to stay healthy during pregnancy.

Essays are written by analyzing the research work of expert writers and institutions. Our reference consists of resources established by authorities in their respective fields. You can learn more about the accuracy of the information we present in our editorial policy.

Leukocytes In Urine

Dr. Miguel Rajio Osorio started his career in 2004 and has 19 years of experience in various fields of gynecology. After two years of internship and community service, she decided to specialize in G&O. Since 2013, Dr. Rezzo has dedicated his training and practice to improving the obstetrical and gynecological health of his patients, earning his degree as a certified specialist… more

Reshmi Das has over four years of experience as a clinical coordinator, medical content writer and medical conference coordinator. His continued interest in medical journals and writing led him to write well-researched articles for it. She writes health and wellness articles for children and pregnant and lactating women. Reshmi completed her Masters in Biotechnology from MITS School of Biotechnology, …Read More

Rebecca is a pregnancy writer and editor with a passion for delivering research-based and engaging content on fertility, pregnancy, birth and post-pregnancy. She completed her graduation in Biotechnology and Genetics from Loyola Academy, Osmania University and a certification in ‘Nutrition and Lifestyle in Pregnancy’ from Ludwig Maximilian University (LMU), Munich. He has health and…more

Anisha holds a Bachelors in Biotechnology from USTM, Meghalaya and a Masters in Applied Microbiology from VIT, Vellore. With two years of experience, he has worked on various research projects in the field of food science. Also, he has internship experience in Oil India Limited as an R&D Project Trainee. As an author, Anisha confirms…more The body’s white blood cells, or leukocytes, help fight infection by identifying and killing invading organisms such as bacteria, viruses, parasites, fungi and other invading microbes. The white blood cell count is a measure of how many of these cells are in your blood. Let’s learn more about high white blood cells and how they can increase the chances of cancer.

High White Blood Cell Count? What You Should Know

A normal count is between 5,000 and 10,000 cells per milliliter (mL) of blood in men and between 4,500 and 11,000 in women. A high white blood cell count can indicate a health problem, but it often indicates inflammation or infection.

It can also signal cancers, including leukemia and lymphoma. When an infection or other inflammatory condition is present, the bone marrow releases more cells to fight it.

There are two types of white blood cells: basophils and eosinophils. Basophils destroy germs and other infections, while eosinophils attack and kill invading organisms and parasites.

A high white blood count can be caused by a variety of conditions, including infections, immune disorders, and cancer. It is important to have a healthcare provider check your white blood cell count as part of your treatment, especially if

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