Causes Of White Blood Cells In Urine But No Infection – What are leukocytes? Surviving in any environment, for any organism, requires adaptability to the surrounding environment, including defense mechanisms. Fortunately, some defense mechanisms are inherited while others are acquired throughout life. The front line of our defense mechanisms in the body is the immune system, which consists of physical barriers such as hair and skin and internal factors including white blood cells. These cells, regardless of their stage of maturation, are called white blood cells or leukocytes. White blood cells are part of the innate immune system and protect the body from disease and infection, so high levels can be an indicator of poor health. The number of leukocytes normally varies from four thousand to eleven thousand in each microliter of blood. Bruce Blaus. When using this image in external sources it may be cited as: Blausen.com staff (2014). “Blausen Medical Medical Gallery 2014”. Wiki Journal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN 2002-4436. – Own work https://commons.wikimedia.org/wiki/File:Blausen_0909_WhiteBloodCells.png Causes of White Blood Cells in Urine It is worth noting that the existence of white blood cells means increased protection reflecting abnormal exposure to external invaders such as infections bacterial or viral, or abnormal cell growth as mentioned in the causes listed below for increased and presence of white blood cells in urine. Urinary tract infections can be caused by bacterial, viral, or parasitic organisms, including: Sexually transmitted infections such as Neisseria gonorrhea and Chladia that first attack the urinary system and urethra1 Hospital-acquired infections, known as nosocomial infections, can result from surgery or catheterization. Bacteria such as Pseudomonas and Staphylococcus aureus are among the causes of hospital-acquired urinary tract infections. Urinary tract stones can cause increased leukocyte counts in the urine, either directly due to irrational inflammation of their chemical components, or through subsequent infection in addition to blockage of their processes. the urinary tract.2 Other causes Cancer, especially that of the urinary tract, and immunological diseases of the kidneys such as systemic lupus can contribute to the increase in white blood cells.3 Inflammations such as chronic prostatitis in people classified as male at birth (AMAB ) and vulvovaginitis in people assigned female at birth (AFAB) can cause an increase in the number of leukocytes in the urine.4, 5 Symptoms The clinical picture of symptoms is considered an informative, rather than exclusive, diagnostic criterion of the process of increasing number of urinary leukocytes. Among these are: 5 Increased body temperature, mild or high fever Tremors as a reflex mechanism of the brain center towards fever Increased frequency of urination Pain or burning sensation during urination Cloudy urine with or without unpleasant odor Lower abdomen, deep pain Urinary discharge, especially in AFAB people due to infection ascending from the genital tract. These secretions may be colored and have an unpleasant odor. Hematuria (blood in the urine) in case of serious infections, urinary tract stones or tumors of the genitourinary tract Who is at greatest risk? People considered to be at high risk are those who have greater exposure to causes and risk factors such as: Sexually active people, especially those who have unprotected sex People with low immunity such as those who are in a coma, have diabetes mellitus or cancer People who depend on high-salt water, such as from wells People admitted to hospitals, especially those undergoing surgical or diagnostic tests related to the urinary tract such as endoscopy or catheterization Cross-contamination between individuals using the same personal items including towels or underwear Diagnosis Diagnosis of leukocytes in urine begins with the analysis of a morning sample of the midstream urine. The sample in the middle of the flow is intended to avoid the collection of contaminants such as surface-living bacteria and skin cells. Urine culture and susceptibility testing can be useful in determining the response of the infectious agent to antibiotic drugs. Urinary tract imaging may be needed to rule out any stones or tumors. This may include tests such as an ultrasound scan of the abdomen, simple X-rays of the urinary tract, computed tomography (CT), and magnetic resonance imaging (MRI). The use of contrast-enhanced images can help to better see the lining of the urinary tract or any obstructions in the urinary tract. Diagnostic endoscopy of the bladder (cystoscopy) and ureters (ureteroscopy) can be very useful in case of suspected masses or even to obtain an additional tissue sample (biopsy). Such methods can also be used in the treatment of urinary tract obstructions. In the case of infections affecting the genital system, a swab of the region can be carried out for further molecular, microbiological and biochemical analyses. Treatment Management of elevated leukocyte levels in the urinary tract relies on both prophylaxis (prevention) and treatment. Home remedies Various hygiene precautions can help prevent the condition: Personal hygiene and effective house cleaning can help prevent inflammation, urinary tract infections and white blood cells in the urine Practice safe sex. The person who has a urinary tract infection should avoid having unprotected sex due to the possibility of having a sexually transmitted disease. Regular follow-up for diabetics with blood glucose level control. Immune support supplements can also help. Over-the-counter pain relievers and anti-inflammatories. Inflammatory agents can be taken to reduce fever Cold compresses can be applied Bathing can help relieve the pain of inflamed areas Various botanical remedies have been suggested6 Medical treatments according to the National Health Service Antibiotics, painkillers, vaginal creams suppositories and vaginal douching according to the severity of the infection. If the infection persists for more than 2 days, broad-spectrum antibiotics such as trimethoprim-sulfamethoxazole, doxycycline and cefotaxime are prescribed. When to see your doctor You should see your doctor if you feel symptoms for more than 2 days or if symptoms occur more than twice in a 6-month period. Also, if there is blood in the urine or severe pain, you should see a doctor. Summary Urine is the kidney’s filtrate of the blood, so the composition of urine can tell us a lot about the state of the urinary tract. White blood cells (leukocytes) in urine can help detect and diagnose a number of conditions including infections (bacterial and viral) and obstructions (e.g., kidney stones, cancer). Reference range values ​​(4-11 thousand per microliter of blood) indicate the health status of the tract. Although elevated leukocyte levels can be indicative of several diseases, most causes are not serious. If pain or inflammation in the abdominal region persists for more than 2 days, or you notice red blood in your urine, ask your doctor for advice. References Wiggins RC, Holmes CH, Andersson M, Ibrahim F, Low N, Horner PJ. Quantification of leukocytes in first collected urine provides new insights into our understanding of symptomatic and asymptomatic urethritis. Int J AIDS. May 2006;17(5):289–95. Crockett-Torabi E, Ward PA. The role of leukocytes in tissue damage. Eur J Anaesthesiol. 1996 May;13(3):235–46. De Boer EC, De Jong WH, Steerenberg PA, Van der Meijden AP, Aarden LA, Debruyne FM, et al. Leukocytes and cytokines in the urine of patients with superficial bladder cancer after intravesical immunotherapy with bacillus Calmette-Guerin. In vivo. 1991;5(6):671–7. Nickel JC, Alexander RB, Schaeffer AJ, Landis JR, Knauss JS, Propert KJ, et al. Leukocytes and bacteria in men with chronic prostatitis/chronic pelvic pain syndrome compared to asymptomatic controls. J Urol. September 2003;170(3):818–22. Huppert JS, Biro F, Lan D, Mortensen JE, Reed J, Slap GB. Urinary Symptoms in Adolescent Women: STI or UTI? J Adolescent Health. 2007 May;40(5):418–24. Das S. Natural therapies for urinary tract infections: a review. Future Journal of Pharmaceutical Sciences [Internet]. 2020 [cited August 21, 2023]; 6(1):64. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498302/.

This content is purely informational and does not constitute medical guidance. It should not replace professional medical advice. Always consult your doctor regarding the risks and benefits of treatment. See our editorial standards for more details.

Causes Of White Blood Cells In Urine But No Infection

We use cookies to ensure that we give you the best experience on our website. If you continue to use this site we will assume that you are happy with it.OkPrivacy PolicyHyaline casts are the simplest and most common type of urinary casts. Urinary casts are microscopic groups of urinary particles, such as cells, fat bodies or microorganisms, enveloped in a protein matrix and present in urine. Urinary casts serve as clinical indicators of kidney condition and can be evaluated to determine how well the kidneys are functioning.

Nephrotic Syndrome In Adults

The kidneys are two bean-shaped organs located in the abdomen, on either side of the lower part of the spine. They are made up of millions of filtering units called nephrons. Each nephron is composed of a glomerulus (a ball-shaped network of blood vessels involved in the formation of urine) and renal tubules (a series of tubules that reabsorb and change the composition of urine as the body needs) .

Cast formation occurs in the final portion of the renal tubules, which consists of the distal convoluted tubules and collecting ducts. It results from the precipitation of the Tamm-Horsfall protein (also known as uromodulin) which is secreted by epithelial tubular cells. The aggregation of the Tamm-Horsfall protein into a protein matrix can then attract the adhesion of other tubular particles (e.g. cells, bile, hemoglobin, albumin, immunoglobulins). Once the urinary casts have developed, they can fall off

Elevated white blood cells in urine but no infection, too many white blood cells in urine but no infection, blood and protein in urine but no infection, white cells in urine but no infection, causes of leukocytes in urine but no infection, causes of white blood cells in urine, red cells in urine but no infection, blood and white cells in urine but no infection, what causes white blood cells in urine but no uti, white and red blood cells in urine but no infection, white blood cells and protein in urine but no infection, white blood cells in dog urine but no infection