Normal Count Of Rbc Wbc And Platelets – Easy tricks to remember common lab values! Covers CBC, chemistry, (BMP/CMP), LFTs, ABG and coagulation studies. Graphics included! Great for nursing, NCLEX and USMLE!
If you enjoyed the memory tricks below, be sure to grab your copy of the study guide so you can review and succeed in medicine!
Contents
Normal Count Of Rbc Wbc And Platelets
With so many different lab tests available, it can be challenging to learn and remember normal values.
Septilin A Polyherbal Formulation Against The Immunosuppression Induced By Cyclophosphamide And Cisplatin In Swiss Albino Mice
We’ve created a list of easy tricks to help you remember normal lab levels for common blood tests.
This is a great review for nursing, NCLEX, and USMLE, as well as any medical student and professional.
You’ll learn tricks for remembering normal lab values for a complete blood count (CBC), chemistry or basic metabolic panel (BMP), comprehensive metabolic panel (CMP), liver function test (LFT), arterial blood gas (ABG), and exam of coagulation.
Let’s review the main components of BMP, as well as tricks to remember their normal values.
Complete Blood Counts (normal Values)
There are usually 3-5 bananas per link and you want to buy them 1/2 off if you can.
Bunions are usually found on the toes or fingers, and we have 5 toes per limb, making a total of 20 toes.
0.9 is right in the middle of normal, and this will help you remember the normal range of 0.6-1.2 mg/dL.
The comprehensive metabolic panel basically adds a liver function panel/test (LFT) to everything in the basic metabolic panel.
Hemorheological Risk Factors Of Acute Chest Syndrome And Painful Vaso Occlusive Crisis In Children With Sickle Cell Disease
Let’s review the main components of the liver function panel, as well as tricks for remembering their normal values.
Another way to think about AST is to use the 9am school start time, and then the average school week is about 40 hours, factoring in homework.
Similar to how we used the “S” in AST to remember school, we’ll use the “L” in ALT to remember labor (work).
The average working day is longer than the school day and can start at 7am and end at 6pm.
Large Immature Cells
Another way to think about ALT is to use a 7am start time for work and then the average work week could be 60 hours.
80 is right in the middle of normal and this will help you remember the normal range of 40-120 U/L.
Normal hemoglobin for women is about 12-16 g/dL and normal hemoglobin for men is about 14-18 g/dL.
When you think of hematocrit, think of hematocrisis and the midlife crisis that usually occurs between the ages of 40-50.
Rbc Blood Test: Normal Ranges And Diagnostic Uses
The main components of ABG that help determine acid-base status include pH, PaCO2, and HCO3 (bicarbonate).
We know that the pH scale ranges from 0-14 and we know that the body likes to be in homeostasis.
You can use ‘pH’ to spell the word ‘Four’ (4) with ‘pH’ instead of ‘F’.
We’re going to multiply 12 by 2, because bi means 2, and that’s going to give us 24.
Normal Platelet Counts Mask Abnormal Thrombopoiesis In Patients With Chronic Myeloid Leukemia.
Coagulation tests are used to assess the blood’s ability to clot and how long it takes for it to clot.
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Late To The Party, But I’m Dancing In Downton Now! (with Lots Of Platelets!)
Previous Previous List of Common Medical Abbreviations and Acronyms Next Next Speech and Language Stages in Pediatrics: NCLEX Chart, Breastfeeding Mnemonics. The evaluation of the blood cell count, i.e. red blood cells (RBC), white blood cells (WBC) or platelets from manual and automated cell counters is central to the diagnosis and treatment of hematological diseases. With only a few exceptions, most of the manual methods have been replaced by automated particle counter methods. The selection of analyzers with a variety of technological principles and techniques is further complicated by the addition of new parameters and their specific utility during the patient care process. The current generation of hematology analyzers is equipped with new and improved specific parameters that are useful to clinicians not only for diagnostic information but also provide invaluable prognostic value for their patients. Many new hematological parameters have been added by instrument manufacturers, some simply with different terminology but with similar clinical value as previously available. Leukocyte Differential Count White blood cells, or leukocytes, are an important part of the body’s immune system because they are responsible for defending the body against infections and invading organisms. The WBC differential determines the percentage of each type of white blood cell present in the blood. The differential can also detect immature white blood cells and abnormalities, both of which are signs of potential problems. There are five types of leukocytes (lymphocytes, monocytes, neutrophils, eosinophils, and basophils). In addition to basophils, they can be visualized on the LMNE matrix (Figure 1) of Yumizen hematology analyzers.
In this matrix, the optical extinction (Y-axis) is plotted against the volumes (X-axis) to form an image of several clusters of cells. Yumizen hematology analyzers are characterized by their capacity to manage precise volumes of whole blood, added to their high level of automation. This allows accurate determination of two additional parameters for leukocyte populations: atypical lymphocytes (ALY) and large immature cells (LIC), reported in percentages as well as absolute numbers. What are large immature cells? LICs are a minor subset of white blood cells that are normally found in the bone marrow tissue where hematopoiesis takes place. This subset consists of various immature forms of myeloid or lymphoid cells combined. Under certain clinical or even physiological conditions, LICs that are not fully matured, especially in terms of their size and complexity, may be released into the peripheral blood. They are thus found to be larger than normal mature blood cells and immature in their nuclear complexity and in the degree of their cytoplasmic granularity. These events occur in both benign (reactive to stress, infection or bone marrow regeneration) and neoplastic diseases (myeloproliferative diseases, leukemias or lymphoproliferative diseases). Among LIC we can find (1): • Promonocytes•Monoblasts•Metamyelocytes • Myelocytes • Promyelocytes• Myeloblasts• Blasts (myeloid or lymphoid) • Prolymphocytes•Megakaryocytes LIC parameter of Yumizen hematology analyzers Several blood diseases have been studied by biologists and the LIC parameter has shown acceptable correlation between automatic and manual counting. This parameter was finally used for flag purposes. we must acknowledge that it is designed to detect and label abnormal cells in the sample by electro-optical attributes and further cytological analysis is needed to provide more information about the patient’s condition. In the high-end, state-of-the-art Yumizen H series instruments from Medical, total LICs are represented as the sum of IMM (immature monocytes), IML (immature lymphocytes), and IMG (immature granulocytes) (2). Such cells, when presented to the analyzer, are identified as a distinct group in the LMNE matrix (Figure 2).
The LIC parameter is used to label samples containing the cell subpopulations mentioned above. The LIC parameter, along with IMM, IML and IMG, is given by the Yumizen H1500 and H2500 for research purposes only (RUO) and should be interpreted with care. However, we have attempted to enhance this additional information provided by the analyst by defining a reference interval for a given population. The study was performed in accordance with the CLSI C28-A3 (Definition, Establishment, and Verification of Reference Intervals in the Clinical Laboratory) guideline. A total of 240 (120 males and 120 females, > 18 years of age) whole blood samples collected in EDTA from apparently healthy Caucasian donors were analyzed in duplicate on three instruments, two Yumizen H2500 and one Yumizen H1500. Samples were kept at room temperature between sampling and testing. The reference interval was defined to include the lower and upper reference limits that encompassed 95% of the values from subjects in the reference population. The results are given in Table 1.
Table 1: Study-defined lower and upper reference limits for the LIC parameter compared to literature values (3, 4).
White Blood Cell
Because values obtained vary by sample population and/or geographic location, it is strongly recommended that each laboratory establish its own normal ranges based on the local population. In this context, according to §5.5.2 of the ISO 15189:2012 standard, the laboratory must determine biological reference intervals or clinical decision values for a specific parameter to validate a test result. The reference intervals are based either on normal values observed after a series of tests in a healthy population or, if it is not possible to use this method, on reliable scientific data. LIC Alarm: The morphological alarm for large immature cells occurs when the number of particles counted in a given area of the LMNE matrix (Figure 1) is higher than the limit set by LIC# or LIC% of particles counted relative to the total number of leukocytes. Based on our internal study and bibliographic data, the alarm values for LIC were set at both 3% and 0.30# (Table 2).
What is their clinical significance? A small number of blasts and poorly differentiated monocytes are usually found in the peripheral blood of healthy individuals (5). During the study, we also observed a higher number of large immature cells in men compared to women. However, their number remains small despite the variability of results sometimes obtained for the same one
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